• Question: do you use the CRISPR process at all in your research? if so do you splice cool genes.

    Asked by anon-182488 to Laurent on 25 Jun 2018. This question was also asked by anon-182472.
    • Photo: Laurent Dupays

      Laurent Dupays answered on 25 Jun 2018:

      I do use CRISPR in my research. As a molecular biologist CRISPR became over the past few years the most important technique used to edit genes. CRISPR made things so much faster that it is a game changing tool.
      The last time I used the technique was to delete a gene’s regulatory region in the mouse DNA. I don’t know if you will consider the gene as cool, but it was Furin. The Furin gene code for a proprotein convertase (!) Basically, some proteins are inactive when they are first made, and must have fragments removed in order to become active. Furin cleaves these fragments and activates the proteins

Comments

  • Photo: Liza

    Liza commented on :

    I don’t use CRISPR yet but I’m looking into the genetics behind why some people react badly to air pollution – maybe in the future I can use CRISPR like Laurent has to try to reduce these bad responses!